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Paul Helquist Selected Research

iejimalide A

3/2010Iejimalides A and B inhibit lysosomal vacuolar H+-ATPase (V-ATPase) activity and induce S-phase arrest and apoptosis in MCF-7 cells.

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Paul Helquist Research Topics

Disease

10Neoplasms (Cancer)
04/2011 - 10/2003
5Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
06/2021 - 10/2009
5Prostatic Neoplasms (Prostate Cancer)
11/2008 - 10/2003
2Rare Diseases (Rare Disease)
10/2013 - 01/2009
2Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
10/2013 - 01/2009
1Disease Progression
10/2019
1Colonic Neoplasms (Colon Cancer)
07/2010
1Breast Neoplasms (Breast Cancer)
03/2010
1Spinal Muscular Atrophy (Progressive Muscular Atrophy)
01/2009
1Muscular Dystrophies (Muscular Dystrophy)
01/2009

Drug/Important Bio-Agent (IBA)

3CholesterolIBA
06/2021 - 01/2012
3Histone Deacetylase InhibitorsIBA
10/2013 - 01/2009
2VorinostatFDA Link
10/2013 - 01/2009
2Protein Tyrosine PhosphatasesIBA
07/2010 - 04/2004
2MacrolidesIBA
03/2010 - 11/2008
2Histone Deacetylases (Histone Deacetylase)IBA
01/2009 - 07/2007
2Biological ProductsIBA
02/2008 - 05/2007
2SiderophoresIBA
02/2008 - 03/2007
1CyclodextrinsIBA
10/2019
1Pharmaceutical PreparationsIBA
10/2013
1LipidsIBA
10/2013
1Carrier Proteins (Binding Protein)IBA
01/2012
1PanobinostatIBA
04/2011
1Sterol Esterase (Hormone-Sensitive Lipase)IBA
07/2010
1CarbamatesIBA
07/2010
1ThiadiazolesIBA
07/2010
1iejimalide AIBA
03/2010
1Adenosine Triphosphatases (ATPase)IBA
03/2010
1Reactive Oxygen Species (Oxygen Radicals)IBA
03/2010
1Cytostatic AgentsIBA
03/2010
1Valproic Acid (Depakote)FDA LinkGeneric
01/2009
1AcidsIBA
01/2009
1iejimalide BIBA
11/2008
1Glutamic Acid (Glutamate)FDA Link
03/2007
1Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)IBA
03/2007
1Protein Isoforms (Isoforms)IBA
04/2004
1Proteins (Proteins, Gene)FDA Link
10/2003
1AntigensIBA
10/2003

Therapy/Procedure

4Therapeutics
07/2010 - 03/2007